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| Literature 2003 |
| 1. |
Abeling, N. G. G. M., M. Duran, H. D. Bakker, A. G. van Cruchten, A. E. M. Stroomer, B. Thöny, N. Blau and B. T. Poll-The (2003). Cerebral methylmalonic aciduria does not exist: a patient with sepiapterin reductase deficiency. Pterins, Folates, and Biogenic Amines in Biology and Medicine. N. Blau and B. Thöny. Heilbronn, SPS Verlagsgesellschaft: 127-131.
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| 2. |
Alp, N. J., S. Mussa, J. Khoo, S. Cai, T. Guzik, A. Jefferson, N. Goh, K. A. Rockett and K. M. Channon (2003). "Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression." J Clin Invest 112(5): 725-35.
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Altindag, Z. Z., T. Baydar, A. B. Engin and G. Sahin (2003). "Effects of the metals on dihydropteridine reductase activity." Toxicol In Vitro 17(5-6): 533-7.
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Andersen, O. A., A. J. Stokka, T. Flatmark and E. Hough (2003). "2.0A Resolution Crystal Structures of the Ternary Complexes of Human Phenylalanine Hydroxylase Catalytic Domain with Tetrahydrobiopterin and 3-(2-Thienyl)-L-alanine or L-Norleucine: Substrate Specificity and Molecular Motions Related to Substrate Binding." J Mol Biol 333(4): 747-57.
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| 5. |
Azumagawa, K., S. Suzuki, T. Tanabe, E. Wakamiya, N. Kawamura and H. Tamai (2003). "Neopterin, biopterin, and nitric oxide concentrations in the cerebrospinal fluid of children with central nervous system infections." Brain Dev 25(3): 200-2.
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Bagi Z, Koller A, Lack of nitric oxide mediation of flow-dependent arteriolar dilation in type I diabetes is restored by sepiapterin, J VASC RES 40 (1): 47-57 JAN-FEB 2003
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Bandmann, O., M. Goertz, J. Zschocke, G. Deuschl, W. Jost, H. Hefter, U. Muller, P. Zofel, G. Hoffmann and W. Oertel (2003). "The phenylalanine loading test in the differential diagnosis of dystonia." Neurology 60(4): 700-702.
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Bassan, A., M. R. Blomberg and P. E. Siegbahn (2003). "Mechanism of Aromatic Hydroxylation by an Activated FeIVdbond;O Core in Tetrahydrobiopterin-Dependent Hydroxylases." Chemistry 9(17): 4055-67.
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Bassan, A., M. R. Blomberg and P. E. Siegbahn (2003). "Mechanism of dioxygen cleavage in tetrahydrobiopterin-dependent amino Acid hydroxylases." Chemistry 9(1): 106-15.
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Ben, J., T. M. Lim, V. P. Phang and W. K. Chan (2003). "Cloning and Tissue Expression of 6-Pyruvoyl Tetrahydropterin Synthase and Xanthine Dehydrogenase from Poecilia reticulata." Mar Biotechnol (NY) 5(6): 568-78.
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Blau N, Bonafé L, Blaskovics ME. "Disorders of phenylalanine and tetrahydrobiopterin metabolism". In: Blau N, Duran M, Blaskovics ME, Gibson KM, eds. Physician's Guide to the Laboratory Diagnosis of Metabolic Diseases. 2nd ed. Heidelberg: Springer-Verlag, 2003: 89-106.
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Blau, N. (2003). "Tetrahydrobiopterin control in phenylketonuria." Genet Med 5(1): 57-8.
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Blau, N., B. Thöny, J. Väsquez Vivar and S. Rajagopalan (2003). "Possible impact of tetrahydrobiopterin and sepiapterin on endothelial dysfunction." Arterioscler Thromb Vasc Biol 23: 913-915.
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Blau, N., C. Bernegger and F. K. Trefz (2003). "Tetrahydrobiopterin-responsive hyperphenylalaninemia due to homozygous mutations in the phenylalanine hydroxylase gene." Eur J Pediatr 162: 196.
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Chen S, Xianwen C, Dehua X, Zhenguo L, Lingfei X, Smith SW, Zhongcheng Z. Behavioral correction of Parkinsonian rats following the transplantation of immortalized fibroblasts genetically modified with TH and GCH genes. Parkinsonism Relat Disord 9 Suppl 2:91-97.2003
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Choi, H. J., S. W. Kim, J. H. Im, S. G. Lee, M. Kim and O. Hwang (2003). "Utilization of exogenous tetrahydrobiopterin in nitric oxide synthesis in human neuroblastoma cell line." Neurosci Lett 352(2): 89-92.
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Choi, H. J., S. W. Kim, S. Y. Lee and O. Hwang (2003). "Dopamine-dependent cytotoxicity of tetrahydrobiopterin: a possible mechanism for selective neurodegeneration in Parkinson's disease." J Neurochem 86(1): 143-52.
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Choi, H. J., S. W. Kim, S. Y. Lee, Y. W. Moon and O. Hwang (2003). "Involvement of apoptosis and calcium mobilization in tetrahydrobiopterin-induced dopaminergic cell death." Exp Neurol 181(2): 281-90.
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Connolly, E. and J. Donlon (2003). "The effects of dietary glycerol on the expression of pterin carbinolamine dehydratase in the rat in vivo." Biochem J Pt.
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| 20. |
Daily psychosocial stressors and cyclic response patterns in urine cortisol and neopterin in a patient with systemic lupus erythematosus. Schubert C, Lampe A, Geser W, Noisternig B, Fuchs D, Konig P, Chamson E, Schussler G PSYCHONEUROENDOCRINOLOGY 28 (3): 459-473 APR 2003
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Das, U. N. (2003). "Folic acid says NO to vascular diseases." Nutrition 19(7-8): 686-92.
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| 22. |
Dhillon, B., M. V. Badiwala, A. Maitland, V. Rao, S. H. Li and S. Verma (2003). "Tetrahydrobiopterin attenuates homocysteine induced endothelial dysfunction." Mol Cell Biochem 247(1-2): 223-7.
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d'Uscio, L. V., S. Milstien, D. Richardson, L. Smith and Z. S. Katusic (2003). "Long-term vitamin C treatment increases vascular tetrahydrobiopterin levels and nitric oxide synthase activity." Circ Res 92(1): 88-95.
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Elzaouk, L., W. Leimbacher, M. Turri, B. Ledermann, K. Bürki, N. Blau and B. Thöny (2003). "Dwarfism and low IGF-1 due to dopamine depletion in Pts-/- mice rescued by feeding neurotransmitter precursors and H4-biopterin." J Biol Chem 278: 28303-28311.
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Erlandsen, H., M. G. Patch, A. Gamez, M. Straub and R. C. Stevens (2003). "Structural Studies on Phenylalanine Hydroxylase and Implications Toward Understanding and Treating Phenylketonuria." Pediatrics 112(6 Part 2): 1557-1565.
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Esberg, L. B. and J. Ren (2003). "Role of nitric oxide, tetrahydrobiopterin and peroxynitrite in glucose toxicity-associated contractile dysfunction in ventricular myocytes." Diabetologia 46(10): 1419-27.
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Franscini, N., N. Blau, A. Schaffner, R. B. Walter and G. Schoedon (2003). "Critical role of interleukin-1beta for transcriptional regulation of endothelial 6-pyruvoly-tetrahydropterin synthase." Arterioscler Thromb Vasc Biol 23: 1990 - 1994.
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Fujimoto, K., M. Sakurai, M. Kawase and S. Katoh (2003). "Effect of antisense oligodeoxynucleotide for sepiapterin reductase on the viability of PC12 cells in the presence of exogenous carbonyl compounds." Chem Biol Interact 143-144: 583-6.
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Gesierich A, Niroomand F, Tiefenbacher CP. Role of human GTP cyclohydrolase I and its regulatory protein in tetrahydrobiopterin metabolism. Basic Res Cardiol 2003;98(2):69-75.
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Gieseg, S. P. and S. Cato (2003). "Inhibition of THP-1 cell-mediated low-density lipoprotein oxidation by the macrophage-synthesised pterin, 7,8-dihydroneopterin." Redox Rep 8(2): 113-5.
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Grosskreutz, Y., H. Betz and M. Kneussel (2003). "Rescue of molybdenum cofactor biosynthesis in gephyrin-deficient mice by a Cnx1 transgene." Biochem Biophys Res Commun 301(2): 450-5.
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Guse, A., C. E. Stevenson, J. Kuper, G. Buchanan, G. Schwarz, G. Giordano, A. Magalon, R. R. Mendel, D. M. Lawson and T. Palmer (2003). "Biochemical and structural analysis of the molybdenum cofactor biosynthesis protein MobA." J Biol Chem.
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Harding, C. O., M. Neff, K. Jones, K. Wild and J. A. Wolff (2003). "Expression of phenylalanine hydroxylase (PAH) in erythrogenic bone marrow does not correct hyperphenylalaninemia in Pahenu2 mice." J Gene Med 5(11): 984-93.
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Hattori, Y., N. Nakanishi, K. Akimoto, M. Yoshida and K. Kasai (2003). "HMG-CoA Reductase Inhibitor Increases GTP Cyclohydrolase I mRNA and Tetrahydrobiopterin in Vascular Endothelial Cells." Arterioscler Thromb Vasc Biol 23(2): 176-182.
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He, A. and J. P. Rosazza (2003). "GTP cyclohydrolase I: purification, characterization, and effects of inhibition on nitric oxide synthase in nocardia species." Appl Environ Microbiol 69(12): 7507-13.
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Heales, S. and A. Lam (2003). "The potential role of astrocyte glutathione and tetrahydrobiopterin in the neurodegenerative process." J Neurochem 85 Suppl 2: 9.
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Hoekstra, R., D. Fekkes, B. J. van de Wetering, L. Pepplinkhuizen and W. M. Verhoeven (2003). "Effect of light therapy on biopterin, neopterin and tryptophan in patients with seasonal affective disorder." Psychiatry Res 120(1): 37-42.
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| 38. |
Hurshman, A. R., C. Krebs, D. E. Edmondson and M. A. Marletta (2003). "Ability of Tetrahydrobiopterin Analogues to Support Catalysis by Inducible Nitric Oxide Synthase: Formation of a Pterin Radical Is Required for Enzyme Activity." Biochemistry 42(45): 13287-13303.
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| 39. |
Hwu, W. L., H. Y. Yeh, S. W. Fang, H. S. Chiang, Y. W. Chiou and Y. M. Lee (2003). "Regulation of GTP cyclohydrolase I by alternative splicing in mononuclear cells." Biochem Biophys Res Commun 306(4): 937-42.
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Hyland, K., R. S. Gunasekara, T. L. Munk-Martin, L. A. Arnold and T. Engle (2003). "The hph-1 mouse: A model for dominantly inherited GTP-cyclohydrolase deficiency." Ann Neurol 54 Suppl 6: S46-8.
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| 41. |
Ichinose, H., T. Ohye, H. Shinotoh, K. Arai, S. Yamazaki, E. Mizuta, S. Kuno and T. Nagatsu (2003). "Biopterin metabolism in patients with malignant syndrome." Parkinsonism Relat Disord 9 Suppl 1: 11-4
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| 42. |
Ihlemann, N., C. Rask-Madsen, A. Perner, H. M. Dominguez, T. S. Hermann, L. Kober and C. Torp-Pedersen (2003). "Tetrahydrobiopterin Restores Endothelial Dysfunction Induced by an Oral Glucose Challenge in Healthy Subjects." Am J Physiol Heart Circ Physiol, online .
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| 43. |
Iino, T., M. Tabata, S. I. Takikawa, H. Sawada, H. Shintaku, S. Ishikura and A. Hara (2003). "Tetrahydrobiopterin is synthesized from 6-pyruvoyl-tetrahydropterin by the human aldo-keto reductase AKR1 family members." Arch Biochem Biophys 416(2): 180-7.
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| 44. |
Iwanaga, N., S. Yamamasu, D. Tachibana, J. Nishio, Y. Nakai, H. Shintaku, M. Imanaka, T. Yamano and O. Ishiko (2003). "Plasma levels of neopterin and biopterin in the umbilical vessels and the maternal vein." Pteridines 14: 1-4.
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| 45. |
Kaneko, Y. S., K. Mori, A. Nakashima, I. Nagatsu and A. Ota (2003). "Peripheral administration of lipopolysaccharide enhances the expression of guanosine triphosphate cyclohydrolase I mRNA in murine locus coeruleus." Neuroscience 116(1): 7-12.
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| 46. |
Karagoz, T., T. Coskun, I. Ozalp, E. Ozkaya and F. Ersoy (2003). "Immune function in children with classical phenylketonuria and tetrahydrobiopterin deficiencies." Indian Pediatr 40(9): 822-33.
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| 47. |
Kawakami, Y., M. Sakamoto, K. Shimada, E. Noguchi, K. Kuwabara, T. Fukui-Kobayashi, K. Shirota, K. Ogawa, T. Fujita, O. Fujino, S. Kojima and Y. Fukunaga (2003). "Correlation between neopterin, biopterin and nitrite/nitrate in cerebrospinal fluid in child patients with neurological diseases." Pteridines 14: 5-8.
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Kim, S. W., Y. J. Jang, J. W. Chang and O. Hwang (2003). "Degeneration of the nigrostriatal pathway and induction of motor deficit by tetrahydrobiopterin: an in vivo model relevant to Parkinson's disease." Neurobiol Dis 13(2): 167-76.
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| 49. |
Kitagami, T., K. Yamada, H. Miura, R. Hashimoto, T. Nabeshima and T. Ohta (2003). "Mechanism of systemically injected interferon-alpha impeding monoamine biosynthesis in rats: role of nitric oxide as a signal crossing the blood-brain barrier." Brain Res 978(1-2): 104-14.
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Koch, R., K. D. Moseley, R. Moats, S. Yano, R. Matalon and F. Guttler (2003). "Danger of high-protein dietary supplements to persons with hyperphenylalaninaemia." J Inherit Metab Dis 26(4): 339-42.
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Kuhn, D. M. and T. J. Geddes (2003). "Tetrahydrobiopterin prevents nitration of tyrosine hydroxylase by peroxynitrite and nitrogen dioxide." Mol Pharmacol 64(4): 946-53.
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| 52. |
Kuzkaya, N., N. Weissmann, D. G. Harrison and S. Dikalov (2003). "Interactions of peroxynitrite, tetrahydrobiopterin, ascorbic acid and thiols:Implications for uncoupling endothelial nitric oxide synthase." J Biol Chem.
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| 53. |
Kwon, H., G. Wu, C. J. Meininger, F. W. Bazer and T. E. Spencer (2003). "Developmental Changes in Nitric Oxide Synthesis in the Ovine Placenta." Biol Reprod (online ahead).
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| 54. |
Landmesser, U., S. Dikalov, S. R. Price, L. McCann, T. Fukai, S. M. Holland, W. E. Mitch and D. G. Harrison (2003). "Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension." J Clin Invest 111(8): 1201-9.
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| 55. |
Leitner, K. L., M. Meyer, W. Leimbacher, A. Peterbauer, S. Hofer, C. Heufler, A. Muller, R. Heller, E. R. Werner, B. Thony and G. Werner-Felmayer (2003). "Low tetrahydrobiopterin biosynthetic capacity of human monocytes is caused by exon skipping in 6-pyruvoyl tetrahydropterin synthase." Biochem J 373(Pt 3): 681-8.
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Leo J. M. Spaapen and M. Estela Rubio-Gozalbo Tetrahydrobiopterin-responsive phenylalanine hydroxylase deficiency, state of the art. (2003) Mol Genet Matab 78: 93-99
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Li, H. Y., Y. M. Yao, Z. G. Shi, N. Dong, Y. Yu, L. R. Lu and Z. Y. Sheng (2003). "Significance of Biopterin Induction in Rats with Postburn Staphylococcus aureus Sepsis." Shock 20(2): 159-65.
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| 58. |
Li, W., D. Knowlton, W. R. Woodward and B. A. Habecker (2003). "Regulation of noradrenergic function by inflammatory cytokines and depolarization." J Neurochem 86(3): 774-83.
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Lindner, M., R. Steinfeld, P. Burgard, A. Schulze, E. Mayatepek and J. Zschocke (2003). "Tetrahydrobiopterin sensitivity in German patients with mild phenylalanine hydroxylase deficiency." Hum Mutat 21(4): 400.
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Linscheid, P., U. Keller, N. Blau, D. J. Schaer and B. Muller (2003). "Diminished production of nitric oxide synthase cofactor tetrahydrobiopterin by rosiglitazone in adipocytes." Biochem Pharmacol 65(4): 593-8.
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Lucke, T., S. Illsinger, C. Aulehla-Scholz, J. Sander and A. M. Das (2003). "BH(4)-sensitive hyperphenylalaninemia. new case and review of literature." Pediatr Neurol 28(3): 228-30.
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Madsen, J. T., P. Jansen, C. Hesslinger, M. Meyer, J. Zimmer and J. B. Gramsbergen (2003). "Tetrahydrobiopterin precursor sepiapterin provides protection against neurotoxicity of 1-methyl-4-phenylpyridinium in nigral slice cultures." J Neurochem 85(1): 214-23.
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Maier, L. A., L. A. Kittle, M. M. Mroz and L. S. Newman (2003). "Beryllium-stimulated neopterin as a diagnostic adjunct in chronic beryllium disease." Am J Ind Med 43(6): 592-601.
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Malo, O., F. Desjardins, J. F. Tanguay, J. C. Tardif, M. Carrier and L. P. Perrault (2003). "Tetrahydrobiopterin and antioxidants reverse the coronary endothelial dysfunction associated with left ventricular hypertrophy in a porcine model." Cardiovasc Res 59(2): 501-511.
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McLuskey, K., J. A. Harrison, A. W. Schuettelkopf, D. H. Boxer and W. N. Hunter (2003). "Insight into the role of escherichia coli MobB in molybdenum cofactor biosynthesis based on the high-resolution crystal structure." J Biol Chem.
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Melichar, B., R. Lenzi, M. Rosenblum, A. P. Kudelka, J. J. Kavanagh, K. Melicharova, S. Templin, M. E. Garcia, J. L. Abbruzzese and R. S. Freedman (2003). "Intraperitoneal fluid neopterin, nitrate, and tryptophan after regional administration of interleukin-12." J Immunother 26(3): 270-6.
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Mitchell, B. M., A. M. Dorrance and R. C. Webb (2003). "GTP cyclohydrolase 1 downregulation contributes to glucocorticoid hypertension in rats." Hypertension 41(3 Pt 2): 669-74.
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Mitchell, B. M., A. M. Dorrance and R. C. Webb (2003). "GTP cyclohydrolase 1 inhibition attenuates vasodilation and increases blood pressure in rats." Am J Physiol Heart Circ Physiol 285(5): H2165-70.
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Mizuma, H., M. Mizutani, S. Nozaki, H. Iizuka, H. Tohyama, N. Nishimura, Y. Watanabe and R. Kohashi (2003). "Improvement by repeated administration of 6R-tetrahydrobiopterin of 5,7-dihydroxytryptamine-induced abnormal behaviors in immature rats." Biochem Biophys Res Commun 302(1): 156-161.
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Murr, C., U. Hainz, E. Asch, P. Berger, B. Jenewein, M. Saurwein-Teissl, B. Grubeck-Loebenstein and D. Fuchs (2003). "Association of increased neopterin production with decreased humoral immunity in the elderly." Exp Gerontol 38(5): 583-7.
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N. Barisic, P. Logan, S. Pikija, D. Skarpa, N. Blau (2003) R208X Mutation in CLN2 Gene Associated with Reduced Cerebrospinal Fluid Pterins in a Girl with Classic Late Infantile Neuronal Ceroid Lipofuscinosis 44: 489-493
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N. Blau, L. Bonafe, I. Krageloh-Mann, B. Thony, L. Kierat, M. Hausler, and V. Ramaekers (2003) Cerebrospinal fluid pterins and folates in Aicardi-Goutieres syndrome: A new phenotype. Neurology ; 61: 642-648
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Nakai, K., M. Urushihara, Y. Kubota and H. Kosaka (2003). "Ascorbate enhances iNOS activity by increasing tetrahydrobiopterin in RAW 264.7 cells." Free Radic Biol Med 35(8): 929-37.
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Nardocci, N., G. Zorzi, N. Blau, E. Fernandez Alvarez, M. Sesta, L. Angelini, M. Pannacci, F. Invernizzi and B. Garavaglia (2003). "Neonatal Dopa-responsive extrapyramidal syndrome in twins with recessive GTPCH deficiency." Neurology 60: 335-337.
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Neopterin as a potential modulator of tumor cell growth and proliferation.. Rieder J, Lirk P, Hoffmann G. MEDICAL HYPOTHESES 60 (4): 531-534 APR 2003
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Pannirselvam, M., V. Simon, S. Verma, T. Anderson and C. R. Triggle (2003). "Chronic oral supplementation with sepiapterin prevents endothelial dysfunction and oxidative stress in small mesenteric arteries from diabetic (db/db) mice." Br J Pharmacol 140(4): 701-6.
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Patarca, R. (2003). "The role of pteridines in physiology and pathology." J Environ Pathol Toxicol Oncol 22(2): 117-27.
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Pi, J., S. Horiguchi, Y. Sun, M. Nikaido, N. Shimojo, T. Hayashi, H. Yamauchi, K. Itoh, M. Yamamoto, G. Sun, M. P. Waalkes and Y. Kumagai (2003). "A potential mechanism for the impairment of nitric oxide formation caused by prolonged oral exposure to arsenate in rabbits." Free Radic Biol Med 35(1): 102-13.
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Podjarny, E., S. Benchetrit, M. Rathaus, A. Pomeranz, G. Rashid, J. Shapira and J. Bernheim (2003). "Effect of tetrahydrobiopterin on blood pressure in rats after subtotal nephrectomy." Nephron Physiol 94(1): P6-9.
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Rebelo, J., G. Auerbach, G. Bader, A. Bracher, H. Nar, C. Hosl, N. Schramek, J. Kaiser, A. Bacher, R. Huber and M. Fischer (2003). "Biosynthesis of pteridines. Reaction mechanism of GTP cyclohydrolase I." J Mol Biol 326(2): 503-16.
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Romstad, A., E. Dupont, B. Krag-Olsen, K. Ostergaard, P. Guldberg and F. Guttler (2003). "Dopa-responsive dystonia and tourette syndrome in a large danish family." Arch Neurol 60(4): 618-22.
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Rudolph, M. J., M. M. Wuebbens, O. Turque, K. V. Rajagopalan and H. Schindelin (2003). "Structural studies of molybdopterin synthase provide insights into its catalytic mechanism." J Biol Chem 278(16): 14514-22.
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Sampaio, M. C. R. and Y. M. Traub-Cseko (2003). "The 245 kb amplified chromosome of Leishmania (V.) braziliensis contains a biopterin transporter gene." MEMORIAS DO INSTITUTO OSWALDO CRUZ 98: 377-378.
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Schallreuter, K. U., S. Kothari, S. Hasse, S. Kauser, N. J. Lindsey, N. C. Gibbons, N. Hibberts and J. M. Wood (2003). "In situ and in vitro evidence for DCoH/HNF-1alpha transcription of tyrosinase in human skin melanocytes." Biochem Biophys Res Commun 301(2): 610-6.
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Segawa, M., Y. Nomura and N. Nishiyama (2003). "Autosomal dominant guanosine triphosphate cyclohydrolase I deficiency (Segawa disease)." Ann Neurol 54 Suppl 6: S32-45.
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Sharma, P., S. A. Raghavan and M. Dikshit (2003). "Role of ascorbate in the regulation of nitric oxide generation by polymorphonuclear leukocytes." Biochem Biophys Res Commun 309(1): 12-7.
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Shimizu, S., K. Shiota, S. Yamamoto, Y. Miyasaka, M. Ishii, T. Watabe, M. Nishida, Y. Mori, T. Yamamoto and Y. Kiuchi (2003). "Hydrogen peroxide stimulates tetrahydrobiopterin synthesis through the induction of GTP-cyclohydrolase I and increases nitric oxide synthase activity in vascular endothelial cells." Free Radic Biol Med 34(10): 1343-52.
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Shimizu, S., Y. Miyasaka, S. Yamamoto, M. Ishii and Y. Kiuchi (2003). "Stimulation of tetrahydrobioptenin synthesis by basic fibroblast growth factor in vascular endothelial cells." Pteridines 14: 9-12.
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Shinozaki, K., A. Kashiwagi, M. Masada and T. Okamura (2003). "Molecular mechanisms of endothelial dysfunction in the insulin-resistant state: the roles of abnormal pteridine metabolism." Pteridines 14: 13-16.
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Shiraishi, H., T. Kato, K. Atsuta, C. Sumi-Ichinose, M. Ohtsuki, M. Itoh, H. Hishida, S. Tada, Y. Udagawa, T. Nagatsu, Y. Hagino, H. Ichinose and T. Nomura (2003). "cGMP Inhibits GTP Cyclohydrolase I Activity and Biosynthesis of Tetrahydrobiopterin in Human Umbilical Vein Endothelial Cells." J Pharmacol Sci 93(3): 265-71.
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Skimming, J. W., O. Nasiroglu, C. J. Huang, C. E. Wood, B. R. Stevens, I. U. Haque, P. O. Scumpia and P. J. Sarcia (2003). "Dexamethasone suppresses iNOS yet induces GTPCH and CAT-2 mRNA expression in rat lungs." Am J Physiol Lung Cell Mol Physiol.
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Solstad, T., A. J. Stokka, O. A. Andersen and T. Flatmark (2003). "Studies on the regulatory properties of the pterin cofactor and dopamine bound at the active site of human phenylalanine hydroxylase." Eur J Biochem 270(5): 981-90.
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Sorlie, M., A. C. Gorren, S. Marchal, T. Shimizu, R. Lange, K. K. Andersson and B. Mayer (2003). "Single-turnover studies of nitric-oxide synthase in the presence of 4-amino-tetrahydrobiopterin: Evidence for a role of tetrahydrobiopterin as a proton donor." J Biol Chem., online ahead publ.
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Steinfeld, R., A. Kohlschutter, K. Ullrich and Z. Lukacs (2003). "A hypothesis on the biochemical mechanism of BH(4)-responsiveness in phenylalanine hydroxylase deficiency." Amino Acids 25(1): 63-8.
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